Relationship Between Apolipoprotein and Alzheimer’s Disease
Apolipoprotein E is a type of protein that is involved in the metabolism of the fats in the body. The protein is implicated in Alzheimer’s disease and cardiovascular conditions. This protein has some interactojn with the low-density protein receptor that is responsible for the processing of the triglyceride-rich protein. The liver produced APOE which belong to a category called lipoprotein.
The work of the lipoprotein is to carry the cholesterol and other fats through the blood as small packages. Lipoprotein are also responsible for the breakdown of the fat. To be specific, APOE, is a component of the low-density lipoprotein. You will need low-density lipoprotein in your body because they will be used for carrying the cholesterol through the bloodstream to the liver for processing. You can therefore easily maintain the normal level of the choretriol in your body and thus preventing the occurrence of the cardiovascular diseases.
The apolipoprotein E has been divided into there main isomers: E2, E3, and E4. All the three form differs very slightly. Almost half of the population have the E3 of the three forms. According to a study, people who have one copy of the E4 tend to have a higher chance of developing Alzheimer’s disease. You chance of getting the disease are more of you inherit two copies of E4. The link between the lipoprotein and the Alzheimer’s disease is not clear. The proteins are going to accelerate the development of the conditions.
The main cause of dementia among the seniors is Alzheimer’s disease. People with dementia progressively losses memory, language, and other cognitive functions. This is because the condition tend to affect the part of the brain that is responsible for cognitive ability. Apolipoprotein E2 is responsible for reducing the risk of getting AD condition.
According to a concluded research, there is some relationship between APOE and cardiovascular disorders. You are at a risk of stroke and heart attack if you have copies of E2. E4 on the other hand has been linked with coronary artery disease.
Studies shows some specific type of people are ideal for this conditions. You are a risk if in your family you have a history of dementia or memory loss. Another sign is a pattern of decreasing intellectual ability. Other symptom is reduction in the language and speech skills not related to other conditions.
After you have gone through this article, you are wondering whether you are at the risk of the Alzheimer’s disease or cardiovascular conditions. The good news is that on the market you will find apolipoprotein E testing kids. One of the best dealer of these testing kits is the Umbrella Scientific. Click on this website to learn more.